Flow cytometry of GATA transcription factors
نویسندگان
چکیده
منابع مشابه
Role of the GATA family of transcription factors in andrology.
Understanding how genes get turned on or off is central to the study of biological processes in both health and disease. Several regulatory mechanisms, which can be positive or negative, have been implicated in the control of tissueand cell-specific gene expression. These include modulation of chromatin structure, DNA methylation, and the regulation of transcription and translation. Transcripti...
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Gene inactivation studies have shown that members of the GATA family of transcription factors are critical for endoderm differentiation in mice, flies and worms, yet how these proteins function in such a conserved developmental context has not been understood. We use in vivo footprinting of mouse embryonic endoderm cells to show that a DNA-binding site for GATA factors is occupied on a liver-sp...
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ژورنال
عنوان ژورنال: Cytometry
سال: 2003
ISSN: 0196-4763,1097-0320
DOI: 10.1002/cyto.b.10047